Route 66 was a hit series on American television at a time when quality television was not uncommon. The series centered around the adventures of two young men who traveled across America, most via the famous Route 66 across the American west all the way to the Pacific at Los Angeles.

The CBS series was weekly from 1960 to 1964. It starred Martin Milner as Tod Stiles and, for two and a half seasons, George Maharis as Buz Murdock.

Maharis was ill for much of the third season, during which time Tod was shown traveling on his own. Tod met Lincoln Case, played by Glenn Corbett, late in the third season, and traveled with him until the end of the fourth and final season.

The series is remembered for its iconic Corvette convertible. Another memorable legacy of the series was the distinctive instrumental theme song composed and performed by Nelson Riddle. It was a big pop hit as well as a major 'turntable' hit on many MOR stations.

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