Christine L BorgmanUniversity of California Los Angeles, USA The role of libraries in E-sciencee-Science, also known as cyberinfrastructure or e-Research, is characterized by dataintensive,information-intensive, distributed, interdisciplinary, and collaborative research.Scholars in all fields are taking advantage of new sources of data and new means topublish and distribute their work online. Content in digital form, whether text fromdigitized books or data from sensor networks, can be mined to ask new questions, in newways. However, the practices, products, and sources of data vary widely betweendisciplines. Some fields are more advantaged than others by the array of content nowonline and by the tools and services available to use it. No longer are data consideredinterim products to be discarded once the research reporting them is published. Rather,they have become important sources of scholarly content to be used and reused. As thedemand for curation of research data accelerates, data repositories may become the newspecial collections for research libraries. The advent of e-Science presents an array ofchallenges and responsibilities for libraries, such as scalable and sustainableinfrastructure, open access to publications and data, and policies for access to data andcomputational resources. This talk will provide an overview of developments in e-Science with specific attention to medical and health libraries.